SIMULTANEOUS DETERMINATION OF PLASMA VOLUME AND TOTAL ERYTHROCYTE QUANTITY WITH CR51 AND I125-ALBUMIN, AND A CONTRIBUTION ABOUT THE RELATIONSHIP BETWEEN PERIPHERAL AND BODY HEMATOCRIT DURING HEMATOLOGIC DISEASES
Abstract
A simple method for the simultaneous estimation of plasma volume and total number of erythrocytes using Cr51 and I125-albumin is described and its advantages over other methods of simultaneous estimation are discussed. The relation between body hematocrit-peripheral hematocrit values was investigated in 35 people. In the control group made up of anaemias of different origin and severity but without enlargement of the spleen and polycythaemics the results were comparable with those using various other methods of blood volume estimations. A highly significant deviation (p<0.001) from the norm was shown in 10 patients with splenomegaly of various origin. Different results were obtained in 3 splenectomized patients. The importance of the changes with regard to the anaemia of patients with splenomegaly and the value of blood volume estimations in various diseases of the blood is discussed.
Document Details
- Document Type
- Technical Report
- Publication Date
- Nov 01, 1966
- Accession Number
- AD0833599
Entities
People
- G. Riccabona
- H. Huber
- K. Keller
Organizations
- United States Army Biological Warfare Laboratories