IMMUNOFLUORESCENCE IN THE DIAGNOSIS OF DIPHTHERIA,

Abstract

The article discusses the importance of the FA method applied as a diagnostic tool in public-health laboratories. A brief history is given of the most outstanding events in the development of fluorescence microscopy. An explanation is given of the technic used for obtaining the diphtheria antiserum by inoculation of rabbits, of the procedure of fractionating the globulins of the antitoxin and the antiserum, and of the conjugation of the latter with fluorescein isothiocyanate. The results obtained are discussed by means of tables. The sensitivity and specificity of the method are determined. (Author)

Document Details

Document Type
Technical Report
Publication Date
Oct 03, 1966
Accession Number
AD0834397

Entities

People

  • Walter F. Arreaga

Organizations

  • United States Army Biological Warfare Laboratories

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Actinomycetales Infections
  • Antitoxins
  • Fluorescence
  • Globulins
  • Health
  • Health Care
  • Immune Serums
  • Inoculation
  • Laser Dyes
  • Medical Specialties
  • Microscopy
  • Public Health
  • Sensitivity
  • Therapy

Readers

  • Chemistry (specifically Chemical Fluorescence)
  • Microbial Pathology
  • Systems Analysis and Design