IMMUNOFLUORESCENCE WITH STREPTOCOCCIC ANTIGENS IN CHRONIC RHEUMATIC MYOCARDITIS

Abstract

In an earlier study it was found that the deposits of gamma-globulin marked on amputated auricles of patients commissurotomized by pure mitralic stenosis, if cemented with fluorescent antistreptolysin sera, reacted immunologically with the latter, thus revealing an antigenic nature of the streptolysinic type. In this study an attempt was made to find out whether the same deposits of gamma-globulin, made to react with streptococcic antigens which had been rendered fluorescent, would reveal an interaction with the same, in this case evidencing also an antibody nature. In 14 out of 26 patients studied it was found that this reaction did indeed occur

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Document Details

Document Type
Technical Report
Publication Date
Sep 22, 1962
Accession Number
AD0834618

Entities

People

  • G. Vacca
  • P. F. Angelino

Organizations

  • United States Army Biological Warfare Laboratories

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Amino Acids Peptides And Proteins
  • Antibodies
  • Biomolecules
  • Biopolymers
  • Cardiomyopathies
  • Chemical Compounds
  • Contractors
  • Diseases And Disorders
  • Gamma Globulin
  • Globulins
  • Governments
  • Intensity
  • Macromolecules
  • Maryland
  • Molecules
  • Pathologic Constriction
  • United States

Fields of Study

  • Biology
  • Medicine

Readers

  • Cardiovascular Physiology
  • Molecular and Cellular Biochemistry
  • Surface Engineering/Surface Coating Technology.