SUBMICROSCOPIC CHANGES IN THE RAT LUNG AFTER ADMINISTRATION OF A CUMARIN DERIVATIVE
Abstract
The changes occurring in the rat lung after administration of the cumarin derivative were examined under the electron microscope. The findings point to increased capillary permeability. Hemorrhages under the tissue of the lung parenchyma are produced not only by a haemorrhagia per diapedesin but also by local vascular wall defects and parenchyma necroses which, in advanced experimental stages, are very extensive and which can even be compared to the so-called cumarin necroses in pharmacotherapy.
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 04, 1966
- Accession Number
- AD0834632
Entities
People
- U. Fuchs
Organizations
- United States Army Biological Warfare Laboratories