THE EFFECT OF A MIXED GAS ATMOSPHERE AT 5 PSIA ON THE INHALATION TOXICITY OF O3 AND NO2
Abstract
A mixed gas atmosphere (68% O2-32% N2) at 5 psia pressure was shown to reduce the acute toxic effect of ozone (O3) in animals when compared with an identical O3 concentration under ambient pressure conditions. The actual reduction of O3 toxicity in the 5 psia-mixed gas environment was not as great as that seen in a 5 psia-100% O2 environment. Further experimentation with increased O2 partial pressures at ambient total pressures led to the conclusion that an increased pO2 of 260 mm Hg was protective against acute O3 effects. No significant differences were seen between 5 psia-mixed gas and 5 psia-100% O2 environments on the effect of nitrogen dioxide (NO2) toxicity in animals although both provide some apparent protection compared with ambient pressure conditions.
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 01, 1967
- Accession Number
- AD0834951
Entities
People
- C. C. Haun
- J. D. Macewen
- J. M. Mcnerney
- R. P. Geckler
Organizations
- Aerojet Rocketdyne Holdings