THE INCIDENCE OF SPECIFIC NEUTRALIZING ANTIBODIES IN THE BLOOD OF INDIVIDUALS EXPOSED TO FOOT-AND-MOUTH VIRUS
Abstract
In the course of the experiments concerning the frequency of neutralizing antibodies in the blood of various persons who had come in contact with the foot-and-mouth virus 38 trial serums were tested, of which 28 were provided by persons who had worked in an infected environment and 10 were provided by persons who had not come in contact with the foot-and-mouth virus, these last subjects serving as a control group. The presence of neutralizing antibodies was established by the serum neutralization method on suckling mice 6 to 8 days old. The data obtained show that there are specific neutralizing antibodies in the blood of persons who have been exposed to foot-and-mouth disease. Among persons working in an infected environment, 54.5 percent were positive subjects while there were no neutralizing antibodies in the persons who had not been exposed to the virus. In the cases studied the disease always took a 'hidden' form; that three persons contracted vesicular stomatitis can not be attributed to the foot-and-mouth virus since the virus could not be isolated from the lymph extracted from the vesicles of these persons.
Document Details
- Document Type
- Technical Report
- Publication Date
- Nov 05, 1965
- Accession Number
- AD0835142
Entities
People
- M. Popa
Organizations
- United States Army Biological Warfare Laboratories