NEUTRALIZATION BY VARIOUS METABOLITES OF THE INHIBITORY EFFECT OF GUANIDINE ON THE DEVELOPMENT OF POLIOVIRUS

Abstract

The development of type I poliovirus in Earle's medium is totally inhibited by .0003M guanidine. Choline, methionine and valine neutralize this effect the mechanism of the action of these antiguanidines is discussed.

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Document Details

Document Type
Technical Report
Publication Date
Nov 29, 1965
Accession Number
AD0835284

Entities

People

  • A. Lwoff
  • M. Lwoff

Organizations

  • United States Army Biological Warfare Laboratories

Tags

DTIC Thesaurus Topics

  • Amines
  • Amino Acids
  • Antiviral Agents
  • Chemistry
  • Culture Media
  • Culture Techniques
  • Export Controls
  • French Language
  • Glutamic Acid
  • Guanidines
  • Infection
  • Inhibition
  • Kinetics
  • Metabolism
  • Metabolites
  • Methionine
  • United States

Fields of Study

  • Biology

Readers

  • Analytical Chemistry
  • Aquatic Ecology
  • Virology (or Medical Virology).