PYRUVATOKINASE, 6-PHOSPHOGLUCONATE DEHYDROGENASE, AND ATP-ASECA ACTIVITY OF RETICULOCYTES AND NORMOCYTES

Abstract

While ATP-ase does not, in the reticulocyte, reveal an activity noticeably different from that of the mature erythrocyte, the 6-phosphogluconate dehydrogenase and the pyruvatokinase reveal a noticeably increased activity. The 6-phosphogluconate dehydrogenase activity, corresponding to the disappearance of the granular and filamentous substance, moves toward the values that are characteristic of the normocyte; this gives noteworthy correspondence between the behavior of the enzyme and the morphological aspect. Pyruvatokinase, instead, decreases more slowly and maintains a still rather high activity in the young erythrocytes which are no longer reticulated.

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Document Details

Document Type
Technical Report
Publication Date
Aug 03, 1964
Accession Number
AD0836163

Entities

People

  • F. Belfiore
  • J. Meldolesi

Organizations

  • United States Army Biological Warfare Laboratories

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Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Biological Laboratories
  • Blood
  • Blood Physiological Phenomena
  • Coefficients
  • Erythrocytes
  • Hematologic Diseases
  • Incubation
  • Italian Language
  • Language
  • Periodicals
  • Physiology
  • Toxic Actions
  • Translations
  • United States

Fields of Study

  • Biology
  • Computer science

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  • Mathematics or Statistics
  • Molecular and Cellular Biochemistry
  • Parasitology and Pharmacology of Malaria.