USE OF SEPHADEX FOR RAPID PURIFICATION OF FLUORESCENCE STAINED ANTIBODY SOLUTIONS

Abstract

Quantitative separation of the unbound fluorescence dye from antibody solutions labelled with fluorescence is achieved by the use of gel filtration with Sephadex G 50. As compared with the previously used dialysis, the purification is terminated in a few minutes and therefore can be done at room temperature. Due to the good possibility of optical control, it permits a regain without loss of the serum conjugate with only negligible decrease of concentration.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1963
Accession Number
AD0836697

Entities

People

  • Michael J. Wagner

Organizations

  • United States Army Biological Warfare Laboratories

Tags

DTIC Thesaurus Topics

  • Absorption
  • Antibodies
  • Availability
  • Biological Laboratories
  • Continents
  • Contractors
  • Dialysis
  • Extinction
  • Filtration
  • Fluorescence
  • Geographic Regions
  • Government (Foreign)
  • Governments
  • Maryland
  • United States
  • West Germany

Fields of Study

  • Physics

Readers

  • Chemistry (specifically Chemical Fluorescence)
  • Mathematics or Statistics
  • Molecular and Cellular Biochemistry