INVESTIGATION CONCERNING THE CAUSE OF DEATH BY APOPLEXY IN ANTHRAX

Abstract

The examination of the nervous system in anthrax is discussed. In anthrax, the degeneration of the neural elements does not proceed evenly in all parts, not even in the same neural nuclei, and the arrival of death should depend upon the localization, the tempo, the intensity and the extent of the appearance of the destructions. The respiratory center is histologically not represented by a group of ganglion cells, nevertheless there is no doubt that lesion of this center causes the sudden death. No other center comes in consideration, in connection with the blood findings, which could be responsible with its functional disorder for such a rapid appearance of death. With tetanus as a neurotropic disease, anthrax has in common that no result is gained from a curative serum therapy, since the vital centers are already affected. That the results with specific anthrax serum can be so multiform and that the curative action is the better the earlier it is administered is completely explainable from this fact. Thus, 100 cc serum when administered in time can have a striking effect, while a dose of more than a liter, given too late, cannot save the life of the animals.

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Document Details

Document Type
Technical Report
Publication Date
Jan 17, 1963
Accession Number
AD0836955

Entities

People

  • F. W. De Moulin

Organizations

  • United States Army Biological Warfare Laboratories

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Animals
  • Blood
  • Brain
  • Cardiovascular System
  • Cells
  • Cellular Structures
  • Cerebral Cortex
  • Death
  • Diseases And Disorders
  • Immune Serums
  • Infection
  • Nervous System
  • Neuroglia
  • Respiration Disorders
  • Rodents
  • Tissues
  • Vaccines

Fields of Study

  • Medicine

Readers

  • Immunology
  • Neuroscience
  • Theoretical Analysis.