THE REACTIVITY OF TUBERCULOUS SKIN AREAS TO TUBERCULIN

Abstract

The specific tuberculous inflammation is developed by an allergic process as a result of apotoxin which is formed from the antigen and antibody. Differences in the intensity of the reaction can arise by a variation of the quantitative relationship between the antigen and the antibody. In freshly inflamed areas, no free antibody is present which could react with the new supply of antigen to form apotoxin, the cause of the inflammation. Following the decline of the inflammation, a local accumulation of antibodies remains. On this area of the skin, more antibody is present than in other, clinically normal, skin areas. This is the reason for the strong reaction of these areas to the introduced antigen. Furthermore, transitions between such extreme cases are also in existence where the primary inflammation is no longer at its peak but is already in a state of regression.

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Document Details

Document Type
Technical Report
Publication Date
Aug 13, 1964
Accession Number
AD0836987

Entities

People

  • Herbert Koch
  • Walter Schiller

Organizations

  • United States Army Biological Warfare Laboratories

Tags

Communities of Interest

  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Antibodies
  • Government (Foreign)
  • Health Services
  • Infection
  • Inflammation
  • Intensity
  • Intervals
  • Observation
  • Plastic Explosives
  • Production
  • Reactivities
  • Skin Tests
  • Therapy
  • Time Intervals
  • Tuberculosis
  • Vaccination
  • Wound Infections

Readers

  • Gulf War Illness and Chronic Multisymptom Illness in Veterans.
  • Immunology
  • Theoretical Analysis.