BIOCHEMICAL TOXICOLOGY OF CA, CS, AND CN
Abstract
The lachrymator agents CA, CS and CN react in vitro and in vivo with biological anions. There is a definite relationship between the in vitro reactions of these agents and their toxicologic effects. In the body the CS- anion complex is further degraded to yield thiocyanate and organic residues. CS releases smooth muscle active substances from tissue not unlike bradykinin. CS aerosol produces a somewhat unique syndrome in dogs characterized by apnea followed by episodic hyperventilation, erythrocytosis, hypothermia, anoxia and acidosis. Recovery by these dogs even from high doses (Ct's) is the rule.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1968
- Accession Number
- AD0837111
Entities
People
- Hubert L.
- Kipling C. Swentzel
- Ronald K. Biskup
- Samuel A. Cucinell
- Stanton C. Loure