CHROMOSOME TRANSFER BETWEEN ESCHERICHIA COLI HFR STRAINS AND PROTEUS MIRABILIS,

Abstract

The successful hybridization of Proteus with E. coli chromosomal genes provides a potentially useful model for studying molecular genetics with a combined genetic and biophysical approach. It is now conceivable to expect that bacterial hybrids consisting of appropriate portions of chromosomal genes derived from various genera will be constructed. Such hybridized strains would be useful for the investigation of virus-bacterial host interactions, the genetics basis of bacterial virulence, evolutionary and taxonomic problems of bacterial identification as well as the development of vaccines. (Author)

Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1968
Accession Number
AD0837120

Entities

People

  • J. A. Wohlhieter
  • L. S. Baron
  • P. Gemski Jr.

Organizations

  • Walter Reed Army Institute of Research

Tags

DTIC Thesaurus Topics

  • Biological Sciences
  • Biology
  • Chromosomes
  • Escherichia
  • Escherichia Coli
  • Genetic Phenomena
  • Genetic Structures
  • Genetics
  • Hybridization
  • Identification
  • Microbial Genetics
  • Molecular Genetics
  • Virulence

Fields of Study

  • Biology

Readers

  • Immunology
  • Molecular Genetics

Technology Areas

  • Biotechnology