HOST INFLUENCE ON THE CHARACTERISTICS OF VENEZUELAN EQUINE ENCEPHALITIS VIRUS

Abstract

One objective of the virus research program is to demonstrate that physiochemical and biological properties of viruses can be altered by selection of, or modification of, the host system in which the virus is propagated, with the ultimate goal of obtaining viral agents whose biological characteristics can be predicted and/or controlled in the growth environment. An approach to this objective was to study the relationship of changes in lipid composition of Venezuelan equine encephalitis (VEE) virus that occur when the virus is propagated in different hosts and to determine if a correlation exists between the changes observed and the biological characteristics of the virus. Comprehensive analyses of the lipid of VEE virus propagated in a number of different hosts were performed.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1968
Accession Number
AD0837129

Entities

People

  • Fred P. Heydrick
  • James X. Dwyer
  • Ralph F. Wachter

Tags

DTIC Thesaurus Topics

  • Acetic Acid
  • Alcohols
  • Biological Sciences
  • Cells
  • Chemistry
  • Chromatography
  • Encephalitis
  • Equine Encephalitis
  • Fatty Acids
  • Gas Chromatography
  • Lipids
  • Methanols
  • Monomolecular Films
  • Paper
  • Propionic Acid
  • Stearic Acid
  • Viruses

Fields of Study

  • Biology

Readers

  • Systems Analysis and Design
  • Virology (or Medical Virology).