THE DEVELOPMENT OF A LABORATORY MODEL FOR THE TRANSMISSION OF AFRICAN TRYPANOSOMIASIS,
Abstract
Glossina austeni can be readily infected with the polymorphic trypanosome, T. brucei (Lugala I) using guinea pigs as donor and recipient hosts and lop-eared rabbits as maintenance hosts. The age of the fly at the time of the infective meal is the most important factor in successful laboratory infections. Day old flies had a midgut infection rate of 27% while less than 1% of the older flies became infected. 3% of day old flies developed salivary gland infections. A complete cyclical transmission of T. brucei was demonstrated. Sufficient replicates of the infection procedures have been performed to indicate that this system should be a useful model for the study of African trypanosomiasis. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1968
- Accession Number
- AD0837175
Entities
People
- Ronald A. Ward
Organizations
- Walter Reed Army Institute of Research