THE USEFULNESS OF THE FLUORESCENT ANTIBODY TECHNIQUE IN STUDYING EXPERIMENTAL NEPHRITIDEDES. ITS POSSIBLE APPLICATIONS TO UNDERSTANDING THE PATHOGENESIS OF SOME HUMAN NEPHROPATHIES
Abstract
The fluorescent antibody technique, applied to the study of experimental nephritis, has provided an obvious proof in favor of the allergic nature of the disease. It has been possible to follow the distribution of the nephrotoxic serum in the organism of the nephritic animal, to prove that it is localized in the kidney and to establish that this serum remains in the tissues for a long period of time. Antibodies stained with fluorescein have also been used to study the altered distribution of globulins of an autochthonous nature in the nephritic animal. The increase in these globulins could indicate a location with an elective antibody concentration.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 01, 1963
- Accession Number
- AD0837216
Entities
People
- Beatrice C. Seegal
Organizations
- United States Army Biological Warfare Laboratories