IMMUNOLOGICAL RELATIONSHIPS BETWEEN PASTEURELLA PESTIS AND PASTEURELLA PSEUDOTUBERCULOSIS,
Abstract
Pasteurella pestis bacteria crossreact serologically with Pasteurella pseudotuberculosis R-sera but not with OH-- or O-sera. The common R-antigen is soluble in water. Virulent plague strains seem to possess a Vi-antigen. A virulent pseudotuberculosis strains gave full protection against massive doses of Pasteurella pestis. The serological relationship between Pasteurella pseudotuberculosis and Pasteurella pestis (R-antigen) has its immunological counterpart. The water-soluble fraction IB of Pasteurella pestis (Baker et al.) contains a component common with Pasteurella pseudotuberculosis (strains of V groups). This component can be eliminated from fraction IB serum either by absorption with Pasteurella pseudotuberculosis bacteria or Pasteurella pestis R-strains. It is suggested that the immunochemically common factor is responsible for the immunity induced. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- May 01, 1965
- Accession Number
- AD0837582
Entities
People
- E. Thal
Organizations
- United States Army Biological Warfare Laboratories