DEMONSTRATION OF ANTHRAX BACILLI AFTER IMMUNIZATION WITH CARBOZOO
Abstract
Eight out of 39 rabbits (20.51%) sacrificed after pre-treatment with bovine or ovine doses of Carbozoo vaccine yielded anthrax bacilli in the edema at the injection site in 4 cases (in 2 cases after 4 hours, in one case after 8 hours, in another after 4 days), in the regional lymph gland in one case (after 5 days) and in all organs in 2 cases (after 4 and 8 days, respectively). In the last 2 cases the rabbits had succumbed to advanced coccidiosis prior to the planned sacrifice and revealed anthrax bacilli in septicemic dissemination. The remaining animals (79.49%), tested a few hours to 14 days after inoculation with Carbozoo, yielded no anthrax bacilli either at the injection site, in the regional lymph gland, or in the spleen, liver, kidneys and the heart blood. The demonstration of precipitinogen in the dried skin of rabbits apparently healthy at the time of sacrifice succeeded in 4 cases, 4 and 36 hours and 2 and 4 days after inoculation, respectively, but only in extracts prepared from skin particles from the site of injection. The occurrence of anthrax bacilli in the milk and urine of 3 cows immunized with Carbozoo could not be observed on the 1st, 2d, 3rd, 4th, 6th, 7th, 8th 9th and 10th day p.i. Nor did supplementary tests produce the pathogen from the injection site of these 3 cows on the 6th, 8th, 9th, 10th and 11th day.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 1968
- Accession Number
- AD0838273
Entities
People
- Christian Troger