A CONTRIBUTION TO THE PICTURE OF THE PATHOMORPHOLOGICAL CHANGES IN HISTOPLASMOSIS. THE FIRST CASES OF HISTOPLASMOSIS OBSERVED IN THE RUMANIAN PEOPLE'S REPUBLIC

Abstract

With regard to the clinical symptomatology there was observed in all three cases a febrile condition that lasted from three weeks to four months with an enlargement of the spleen and anemia with leukopenia, whereupon the lethal termination occurred in a condition of emaciation. These clinical symptoms are considered typical for the severe disease. The diagnosis of histoplasmosis was established microscopically as a result of discovering yeast-like bodies and also Histoplasma capsulatum in the reticulo-endothelial cells of the tissues, particularly in the lungs. In the lung tissue, in addition to fungus spores, the presence of numerous treadlike mycelia was detected along with pseudomycelia and the formation of blastospores (or arthrospores).

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Jul 01, 1968
Accession Number
AD0838275

Entities

People

  • A. Mureshanu

Tags

DTIC Thesaurus Topics

  • Animals
  • Cancer
  • Cells
  • Connective Tissue
  • Diseases And Disorders
  • Endothelial Cells
  • Fungi
  • Gram-Negative Bacterial Infections
  • Health Services
  • Infectious Diseases
  • Lung
  • Materials
  • Tissues
  • Tuberculosis

Readers

  • Immunology