ANTIMICROBIAN ACTIVITY OF CHLORPROMAZINE, ANTAGONISTIC ACTION OF ADENOSINE-5 TRIPHOSPHATE (ATP) AND SOME ELECTRONIC ASPECTS OF THOSE ACTIONS

Abstract

A study was made of the antimicrobian activity of chlorpromazine, which theoretical chemistry calculations represent as a strong donor of electrons. The antagonistic action of adenosine-5 tiphosphate (ATP) was also shown. Its addition to a culture of staphylococci which had been arrested by chlorpromazyne makes possible the renewal of growth. The lyse of the same germ by an appropriate phage, decelerated by chlorpromazine, was accelerated by a simultaneous addition of biliverdin, a substance presenting the properties of a good acceptor of electrons.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 1962
Accession Number
AD0839358

Entities

People

  • Jacques Trefouel

Organizations

  • United States Army Biological Warfare Laboratories

Tags

Communities of Interest

  • Energy and Power Technologies

DTIC Thesaurus Topics

  • Adenosine
  • Biliverdin
  • Calorific Value
  • Central Nervous System
  • Chemical Synthesis
  • Chemistry
  • Chlorpromazine
  • Computational Chemistry
  • Electron Acceptors
  • Electron Donors
  • Electrons
  • Ionization Potentials
  • Nervous System
  • New York
  • Organic Chemistry
  • United States

Readers

  • Immunology
  • Parasitology and Pharmacology of Malaria.

Technology Areas

  • Microelectronics