METABOLISM DURING TYPHUS CONVALESCENCE
Abstract
The peculiarities of metabolism among typhus convalescents may be attributed to two factors: (1) An increase in the oxidation processes as related to substances free from nitrogen has the following results: (a) fat deposits are reduced; (b) an albumin saving effect becomes particularly eclatant upon increasing the supply. This albumin saving effect of the food free from nitrogen is far more pronounced at the advanced stage of convalescence than at its beginning. (2) During the early phases of convalescence, the peculiarities of the typhus albumin exchange becomes the determining factor, the sole responsible factor, or, during the normal fever diet, in moving toward a low value. The difference between the albumin introduced and this somewhat 'critical' status of the albumin decomposition is the only factor determining the amount of albumin retention, since albumin metabolism, although it has reached this low point, has lost its own excitability, i.e., its ability to react to an increase in supply with augmented decomposition, and only regains this capacity during the convalescence. Therefore, there exists an antagonistic relationship between these two components of metabolism whose resultant is an increase in the rapid albumin retention rate.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 19, 1965
- Accession Number
- AD0839376
Entities
People
- H. Benedict
- N. Suranyi
Organizations
- United States Army Biological Warfare Laboratories