OXYGEN CONSUMPTION OF THE ISOLATED PERFUSED LUNG LOBE OF THE DOG
Abstract
The O2 consumption of the isolated dog lung lobe perfused with blood from a donor dog was investigated. The lung lobe had been made atelectatic and filled with Ringer's solution. The arterio-venous O2 pressure difference was measured by polarography. The average O2 consumption of 11 lung lobes was 0.025 ml/min(g) of dry weight. There was no significant difference in O2 consumption between lung lobes perfused with arterial blood (pO2 = 340-550 mm Hg) and those perfused with venous blood (pO2 = 55-90 mm Hg). Variation of the perfusion rate between 350 ml/min (approx. normal value) and 30 ml/min did not change the O2 consumption. Lowering the arterial blood pressure of the donor dog by hemorrhage had no effect upon the magnitude of the O2 consumption of the isolated lung lobe.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 02, 1967
- Accession Number
- AD0840399
Entities
People
- Johannes Piiper
- Ryosaku Kusachi