STUDY OF THE ACTION OF SODIUM LAURYLSULFATE ON E. COLI

Abstract

Sodium laurylsulfate (L.S.) lyses E. coli cells when their metabolism is halted or inhibited by any of a number of antimetabolites. Actively growing cells are completely unaffected. It was shown by paper chromatography that L.S. extracts the lipoprotein of free cell walls exactly as phenol does. L.S. has an extremely rapid lytic action on globular forms of E. coli. The probable mechanism of the cytolysis of nonmetabolizing whole cells is discussed.

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Document Details

Document Type
Technical Report
Publication Date
Jan 24, 1967
Accession Number
AD0840452

Entities

People

  • A. Bolle
  • E. Kellenberger

Organizations

  • United States Army Biological Warfare Laboratories

Tags

Communities of Interest

  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Acids
  • Aeration
  • Amino Acids
  • Anti-Bacterial Agents
  • Bacteria
  • Biological Laboratories
  • Buffers (Chemistry)
  • Cell Membrane
  • Cells
  • Cells (Biology)
  • Cellular Structures
  • Chemistry
  • Electron Microscopes
  • Inhibitors
  • Lipopolysaccharides
  • Measurement
  • Walls

Readers

  • Aerospace Research.
  • Molecular and Cellular Biochemistry