IMMUNIZATION OF WHITE MICE TO ECTROMELIA WITH VACCINE VIRUS - II
Abstract
Intrapertioneal booster inoculation of vaccine virus (strain 'Ankara') renews immunization to induced intraperitoneal ectromelia infection. The protection of the booster shot becomes attenuated during the same interval of time as that of the initial vaccination, i.e. 12 to 26 weeks. Intraperitoneal administration of appropriate doses of commercially available vaccine lymph and/ or tissue-culture vaccine produces the same immunization to induced intraperitoneal ectromelia infection as the inoculum from vaccine (strain 'Ankara') infected chorio-allantois membranes. Intraperitoneal vaccination increases the survival rate of a stock of mice with latent ectromelia as against non-vaccinated controls of the same stock. Female mice develop a higher immunity than male animals.
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 24, 1968
- Accession Number
- AD0840531
Entities
People
- G. Reckzeh
- H. Zeller
Organizations
- United States Army Biological Warfare Laboratories