IMMUNIZATION OF WHITE MICE TO ECTROMELIA WITH VACCINE VIRUS

Abstract

Immunization to inoculated infectious ectromelia can be provided by intraperitoneal or intravenous administration of vaccine virus ('Ankara' strain) in suitable dilution. The degree of immunization depends on the dose administered. After peritoneal injection of vaccine virus, distinct immunization can be demonstrated within three days and immunity is established after six days. Five months after a single injection of vaccine virus, more than 50% of the test animals still show immunity to a massive injection of ectromelia virus.

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Document Details

Document Type
Technical Report
Publication Date
Apr 24, 1968
Accession Number
AD0840564

Entities

People

  • G. Reckzeh
  • H. Zeller

Organizations

  • United States Army Biological Warfare Laboratories

Tags

DTIC Thesaurus Topics

  • Anti-Bacterial Agents
  • Chlorides
  • Dilution
  • Diseases And Disorders
  • Immunity
  • Immunization
  • Infection
  • Infection Control
  • Membranes
  • Musculoskeletal Abnormalities
  • Sodium Compounds
  • Tissues
  • Vaccination
  • Vaccines
  • Virus Diseases
  • Viruses
  • Wound Infections

Fields of Study

  • Biology

Readers

  • Infectious Disease/Epidemiology
  • Parasitology and Pharmacology of Malaria.
  • Toxicology/Environmental Toxicology

Technology Areas

  • Biotechnology