THE BINDING OF SOLUBLE ANTIGEN-ANTIBODY COMPLEXES TO ERYTHROCYTES

Abstract

The surface of erythrocytes adsorbs soluble antigen-antibody complexes to a greater extent than it does either of the two components of the complex separately. Human albumin and rabbit antihuman-albumin antibody were investigated as a model of a soluble antigen-antibody complex. The specific concentration of the immune complex at the red cell surface suggests that these cells are actively involved in the removal of antigen-antibody complexes from the circulation.

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Document Details

Document Type
Technical Report
Publication Date
Apr 24, 1967
Accession Number
AD0840850

Entities

People

  • F. Gramlich
  • H. E. Mueller

Organizations

  • United States Army Biological Warfare Laboratories

Tags

DTIC Thesaurus Topics

  • Adsorption
  • Antibodies
  • Antigen-Antibody Complex
  • Antigens
  • Blood
  • Blood Plasma
  • Blood Proteins
  • Buffers (Chemistry)
  • Cells
  • Erythrocytes
  • Films
  • Gamma Globulin
  • Globulins
  • Macromolecules
  • Molecules
  • Proteins
  • United States

Fields of Study

  • Biology
  • Medicine

Readers

  • Molecular and Cellular Biochemistry