FURTHER STUDIES ON THE METABOLISM OF PROTEUS VULGARIS; ITS STABLE L-PHASE AND THE PLEUROPNEUMONIA-LIKE ORGANISMS

Abstract

By using manometric respiration measurements it was determined that the stable L-phase of P. vulgaris utilized the same substrates as does the bacteria from which it was isolated. The sensitivity to various poisons is also the same (with some minor deviations). Eight strains of PPLO oxidized only a few carbohydrated and then minimally; no organic acids, amino acids and alcohols. They are resistant to high doses of KCN, DNP, azide, arsenite and arsenate. Implications are that they possess other enzyme systems for substrate degradation than do most other organisms. Because of high sensitivity to iodoacetate and fluoride it may be assumed that degradation is via the Embden-Meyerhof pathway to pyruvic acid.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 1968
Accession Number
AD0841141

Entities

People

  • C. Zehender
  • James M. Mueller
  • O. Kandler

Tags

Communities of Interest

  • Air Platforms

DTIC Thesaurus Topics

  • Acids
  • Alcohols
  • Amino Acids
  • Arsenates
  • Bacteria
  • Carbohydrates
  • Citric Acid
  • Degradation
  • Fluorides
  • German Language
  • Measurement
  • Metabolism
  • Organic Acids
  • Pyruvic Acid
  • Respiration
  • Sensitivity
  • Substrates

Readers

  • Aquatic Ecology
  • Molecular and Cellular Biochemistry
  • Organic Chemistry