THE CULTURE OF CELLS FROM A 'CLOISONNE' GOAT KIDNEY.

Abstract

A study was made of comparative in vitro growth patterns of the 'cloisonne' and normal goat kidneys (Capra hircus) over long term cell cultivation. Strikingly different in gross appearance and microscopic analysis, each continues this distinctly dissimilar pattern in tissue culture. Pigmented thickening of renal basement membranes of the proximal convoluted tubules in the cortex of the 'cloisonne' kidney reveals evidence of possible continued production in vitro. Although possessing a well-defined pathological phenomenon in vitro, substantiated by electron microscopy, the 'cloisonne' kidney cell retains normal chromosome counts throughout serial subculture. Its counterpart, the normal control culture, continues its active proliferation without any of the abnormal morphological features found in the 'cloisonne' culture. (Author)

Document Details

Document Type
Technical Report
Publication Date
Jul 01, 1968
Accession Number
AD0841340

Entities

People

  • William O. Wood

Tags

DTIC Thesaurus Topics

  • Anatomy
  • Basements
  • Biological Sciences
  • Cells
  • Chromosomes
  • Electron Microscopy
  • Electrons
  • Membranes
  • Microscopy
  • Optical Analysis
  • Production
  • Tissue Culture
  • Tissues

Fields of Study

  • Medicine

Readers

  • Molecular and Cellular Biochemistry
  • Systems Analysis and Design
  • Toxicology/Environmental Toxicology

Technology Areas

  • Microelectronics