Serological Diagnosis of Syphilis. Recent Achievements: Reither's Treponemic Antigen, Immunofluorescence
Abstract
In treated syphilis, IF has a sensitivity equal to that of Nelson's test; as to RPCF, its indication in this case is superior to that obtained with classical cardiolipid serology. These two methods have not reached their full maturity; improvements are necessary to obtain a sure and irreprochable technique (elimination of nonspecific antibodies: globulins of indeterminate nature in the serum of some subjects; in IF standardization of material and techniques; very limited activity zone for RPCF...). Also, today, it would not be a question of substituting these techniques for the hemolysis and floculation reactions on one hand, and for Nelson's test on the other hand; they must collaborate between themselves. And in the absence of a TPI, these two reactions can be performed in a current analysis laboratory and give the Biologist and Clinician appreciable results which they could not expect before the coming of these treponema reactions.
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 03, 1968
- Accession Number
- AD0843450
Entities
People
- R. Frot
Organizations
- United States Army Biological Warfare Laboratories