Serology and Immunology as Aids in Diagnosis of Syphilis

Abstract

There are remarkable facilities for serological reactions applicable to diagnosis of syphilis. In practice one should choose a limited number of reactions done with strict technical exactness in the presence of adequate controls. In the vast majority of cases, the cardiolipidic reactions answer to the requirements of clinical examination and epidemiology. The Nelson test -- of remarkable specificity and used especially for study of litigous cases -- remains the reference reaction. After a long period of isolation, the serology of syphilis has come back into the framework of immunology of bacterial maladies. The presence of antibodies is linked to the presence of the treponema. However, no serological method, no matter how highly perfected, is completely immune from failure. Only close cooperation between clinician and biologist gives to serodiagnosis of syphilis all its significance and value.

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Document Details

Document Type
Technical Report
Publication Date
Jan 30, 1968
Accession Number
AD0843452

Entities

People

  • G. Daguet

Organizations

  • United States Army Biological Warfare Laboratories

Tags

DTIC Thesaurus Topics

  • Agglutination
  • Allergy And Immunology
  • Animals
  • Anti-Bacterial Agents
  • Bacteria
  • Blood
  • Gram-Negative Bacterial Infections
  • Infection
  • Lepidoptera
  • Light Sources
  • Microorganisms
  • Molecules
  • Proteins
  • Sexually Transmitted Diseases
  • Syphilis
  • Tissue Extracts
  • United States

Fields of Study

  • Biology
  • Medicine

Readers

  • Immunology
  • Infectious Disease/Epidemiology
  • Systems Analysis and Design