Reticular Cell Response in the Rabbit Appendix to Autologous and Homologous Transplants
Abstract
A progressive increase in the number and confluency of reticular cells was observed in the lymphoid portion of the appendix of rabbits following transplantation of homologous thymus beneath the kidney capsule. These changes were most striking at 96 hours following transplantation. Similar, but less severe, changes were also found in the sacculus rotundus but were not seen in other intestinal lymphoid tissue, peripheral lymph nodes, spleen, or recipient thymus. Significant reactive changes were not seen following homologous muscle transplants or autografts of either thymic or muscle tissue. These studies indicate that the appendiceal reticular reaction may be nonspecific and in part represent a transplantation reaction. The results of histochemical studies suggest that these reactive cells have neither macrophage-like nor active protein synthetic functions.
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 01, 1968
- Accession Number
- AD0843467
Entities
People
- Alfred C. Standen
- Bjarne Pearson
- John R. Esterly