Varying Behavior of Pasteurella-Phages
Abstract
The behavior of two strains of Past. pseudotuberculosis-phages and two others described as Past. pestis-phages one of which (PTB-phage) was adapted to Past. pseudotuberculosis was studied in regard to thermic (56-75C) and chemical factors (phenol, chloroform, merthiolate, formalin, pH 3-9). Also, cross-wise neutralization- and inactivation-tests with phage-immunsera were carried out. The results show that the Past. pseudotuberculosis-phage called PST-phage is more resistant to temperatures of 56-65C and to solutions with pH 4.0 to 5.0 than the three Y-, PTB- and R- strains described as Past. pestis- or Past. pseudotuberculosis-phages and which reacted alike. The difference in the behavior of PST- and Y-phages on one hand and the uniform behavior of Y-, PTB- and R- phages on the other hand suggest that the R-phages also represent a primary strain of Past. pestis-phages which is adapted to Past. pseudotuberculosis. Further experiments have to be done to show whether this varying behavior is common to a larger number of Past. pestis and Past. pseudotuberculosis-phages.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 1968
- Accession Number
- AD0843841
Entities
People
- W. Knapp
Organizations
- United States Army Biological Warfare Laboratories