Methods and Utilization of Freeze-Drying
Abstract
The anatomist Altmann of Leipzig in 1890 probably was the first to utilize freeze-drying in the solution of biological problems by desiccating tissues for microscopic examination. He took advantage of the fact that tissue particles retain their structure in nearly unaltered form upon rapid freezing and drying, so that fixation in liquid chemicals, which causes artifacts, could be circumvented. This method of preparing tissue for microscopic or electron- microscopic examination currently has found acceptance in numerous institutes.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 1968
- Accession Number
- AD0843937
Entities
People
- G. Matz
- K. Neumann
Organizations
- United States Army Biological Warfare Laboratories