Urinary Hydroxyproline and Circulating HGH Preliminary Findings in Some Endocrine Diseases
Abstract
The relationships between the concentration of circulating HGH and the urinary excretion of hydroxyproline were studied in 71 subjects, including 40 with diabetes mellitus, 11 with acromegaly, and 20 who were clinically healthy. It was demonstrated that in patients with diabetes mellitus the urinary excretion of hydroxyproline is often greater than the average figures recorded in the controls. This increase is more marked in youthful diabetes, in other words, where the metabolic disorder is more severe and unstable. On the other hand, in patients in whom the acromegaly syndrome was complicated by obvious disorders in glycidic exchange, the excretion of the imino acid appears particularly pronounced: it is very much greater than the--by the way in themselves rather high--values that are typical of acromegaly not connected with diabetes mellitus.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 06, 1969
- Accession Number
- AD0845941
Entities
People
- I. Isidori
- L. Sereno
- O. Recchia