Observations and Investigations on Contagious Pustular Dermatitis (Echthyma Contagiosum) of Sheep as a Human Disease (Beobachtungen und Untersuchungen ueber den Lippengrind (Ecthyma Contagiosum) der Schafe als Zooanthroponose)

Abstract

Ecthyma virus (contagious pustular dermatitis virus) of humans as well as ovine (sheep) origin have been isolated and serially passed in tissue cultures of calf testes cells. After growth in tissue culture, the sheep virus strain was shown to be the contagious agent that causes echthyma by transmission studies to sheep. Cross-immunity tests were carried out with the sheep virus strain and a human cytopathogenic agent suspected to the ecthyma virus. The human strain was derived from a veterinary student who had recently been in contact with naturally-infected sheep and later developed pustules on his finers which resembled milker's nodes. Three other cases of human ecthyma infections, susposedly contracted from the same animal source, were observed and have been reported on. By means of cross immunity tests in sheep, the immunological identity of both the ovine and human virus strains could be demonstrated.

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Document Details

Document Type
Technical Report
Publication Date
Nov 01, 1968
Accession Number
AD0845943

Entities

People

  • Bernd Liess

Organizations

  • United States Army Biological Warfare Laboratories

Tags

DTIC Thesaurus Topics

  • Antibodies
  • Blood
  • Buffers (Chemistry)
  • Cells
  • Culture Techniques
  • Dermatitis
  • Diseases And Disorders
  • Infection
  • Infectious Diseases
  • Lymphatic System
  • Materials
  • Membranes
  • Resistance
  • Skin Diseases
  • Spores
  • Tissue Culture
  • Wound Infections

Readers

  • Immunology
  • Infectious Disease/Epidemiology
  • Snow Cover Descriptors for Reptiles and Their Illustrations.