Antigenicity of Psittacosis Vaccines Killed by Ionizing Radiation,
Abstract
Exposure of suspensions of the Borg strain of Chlamydia psittaci to graded doses of gamma radiation resulted in loss of infectivity. Exposure in the frozen state produced slower loss of infectivity than exposure in the fluid state; doses of 400,000 r and 250,000 r, respectively, were required for complete loss of detectable infectivity. Both reactions deviated moderately from first-order behavior. The frozen suspensions retained greater antigenicity for mice than did the fluid suspensions and were also more antigenic than suspensions killed by treatment with formaldehyde. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 01, 1969
- Accession Number
- AD0850074
Entities
People
- George G. Wright
- John R. Mitzel
- Norman S. Swack