Foot and Mouth Disease Vaccine Prepared from Virus Cultivated in Calf Kidney Cell Suspension

Abstract

Five series of foot and mouth disease vaccine were prepared in calf kidney cell suspensions. Three were highly active, protecting all vaccinated cattle from controlled infection. One series was satisfactory, protecting three out of four animals, with no evidence of generalized disease. One series was less effective, with one example of generalized disease. Culturing in calf kidney cell suspensions allows one to obtain large quantities of foot and mouth disease virus more easily than the monolayer culture method.

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Document Details

Document Type
Technical Report
Publication Date
Mar 12, 1969
Accession Number
AD0851106

Entities

People

  • I. V. Zvyagin
  • N. V. Kazantseva
  • N. V. Likhachev
  • N. Y. Zueva
  • R. A. Makhnyuk
  • S. D. Sankov
  • T. L. Fyedrova
  • V. A. Molochnikov

Organizations

  • United States Army Foreign Science and Technology Center

Tags

DTIC Thesaurus Topics

  • Aluminum Oxides
  • Buffers (Chemistry)
  • Diseases And Disorders
  • Government (Foreign)
  • Governments
  • Infection
  • Materials
  • Mixing
  • Monomolecular Films
  • Mouth Diseases
  • Sodium Compounds
  • Tissue Culture
  • Tissues
  • Translations
  • Vaccines
  • Wound Infections

Fields of Study

  • Biology

Readers

  • Riverine Ecology
  • Systems Analysis and Design
  • Virology (or Medical Virology).

Technology Areas

  • Biotechnology