Interference Between Coxsackie Viruses of the Same Type (Interference Entre Virus Coxsackie de Meme Type)
Abstract
A strain of Coxsackie virus B5 and a variant from that strain were studied to determine interference phenomenon between the two strains. Results of studies demonstrated the following: With weak doses of interfering and 'challenger' virus, 15 minutes of lead-time is sufficient to produce about 50% of interference. The interference produced by small amounts of interfering virus can be overcome. This is still possible even after a lead-time of 60 minutes for the interfering virus when the quantity of 'challenger' virus is increased sufficiently. It is concluded, therefore, that a strain of interfering virus, restricted to slow development, during the first 15 minutes of its cycle of reproduction is capable of restricting the development of a second virus of the same type.
Document Details
- Document Type
- Technical Report
- Publication Date
- May 01, 1969
- Accession Number
- AD0854028
Entities
People
- G. Pieroni
- J. Charrel
- P. Gevaudan
Organizations
- United States Army Biological Warfare Laboratories