Nitrosoguanidine Mutagenesis and Chromosomal Replication in Staphylococcus Aureus

Abstract

The number of mutations induced by nitrosoguanidine per 1,000,000 survivors is the same for exponential cells as for cells with resting, complete chromosomes. During synchronous chromosomal replication, no peak of mutations per million survivors appears at the time of duplication of the genes examined. It was concluded that for Staphylococcus aureus the replicating region of the chromosome is no more susceptible to nitrosoguanidine mutation than is the resting chromosome.

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Document Details

Document Type
Technical Report
Publication Date
May 01, 1969
Accession Number
AD0854130

Entities

People

  • Robert A. Altenbern

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Bacteria
  • Bacteriology
  • Biological Sciences
  • Cells
  • Chromosomes
  • Continents
  • Escherichia
  • Escherichia Coli
  • Government (Foreign)
  • Microorganisms
  • Mutations
  • New York
  • Nitroso Compounds
  • Staphylococcus Aureus
  • Test Methods
  • United States
  • United States Government

Fields of Study

  • Biology

Readers

  • Military/Explosive Ordnance Disposal (EOD) Technology
  • Molecular and genetic basis of cancer.