Controlled Oxidation-Reduction Potential in Submerged Tissue Culture Fermentation in Pilot-Scale Fermentors,

Abstract

Operations of a submerged tissue culture pilot facility are presented. Oxidation-reduction potential (ORP) was controlled, and its effects on fermentation are discussed. A strain of Earle's L cells was grown to as high as 4400000 viable cells per ml. Cultures were grown without the aid of antibiotics. An internal standard was developed to calibrate the redox measuring system. (Author)

Document Details

Document Type
Technical Report
Publication Date
Sep 01, 1969
Accession Number
AD0860413

Entities

People

  • Carlton C. Wiles
  • Vernon C. Smith

Tags

DTIC Thesaurus Topics

  • Anti-Bacterial Agents
  • Chemical Reactions
  • Fermentation
  • Oxidation
  • Standards
  • Tissue Culture

Readers

  • Aerospace Test and Evaluation
  • Electrochemical Surface Science
  • Microbial Pathology