Multiplication of the Neurotropic Strain of Rift Valley Fever in the Mouse Spleen and Liver

Abstract

The neurotropic strain of Rift Valley fever virus multiplied in the spleen and liver of mice injected with it intraperitoneally. Virus was detected in the spleen 41 days after injection. Virus was detected for several days in the circulating blood even after the appearance of neutralizing antibodies. After serial passage in the mouse liver, very low doses of virus injected intraperitoneally killed mice with nervous symptoms.

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Document Details

Document Type
Technical Report
Publication Date
Nov 05, 1969
Accession Number
AD0863673

Entities

People

  • Ichiro Nishi
  • Minoru Matumoto
  • Yasuo Saburi

Tags

DTIC Thesaurus Topics

  • Antibodies
  • Emulsions
  • Export Controls
  • Government (Foreign)
  • Governments
  • Infection
  • Inoculation
  • Intervals
  • Materials
  • Rift Valley Fever
  • Rift Valleys
  • Tissue Culture
  • Translations
  • Valleys
  • Virulence
  • Viruses

Fields of Study

  • Biology

Readers

  • Immunology