New Method for the Quick Recognition of the Cholera Vibrio and the Typhoid Bacillus

Abstract

The blood serum (and the peritoneal lymph) of a guinea pig immunized against cholera has a very striking specific effect--previously overlooked or not appreciated--on the cholera vibrio, likewise the serum of an animal immunized against typhoid on the typhoid bacterium, etc. If one adds the appropriate protective serum to the floating suspension of the agar culture of one of the mentioned types of bacteria, the bacteria are seen to conglutinate into big balls, and the spontaneous movement comes to a standstill. These effects are connected in the closest manner with the protective action of the sera. They are the consequences of the fact that the bacteria become sticky under the impact of the antibodies contained in the immune serum. The specific substances of the immune sera are labeled conglutinants or agglutinins.

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Document Details

Document Type
Technical Report
Publication Date
Jun 26, 1970
Accession Number
AD0872846

Entities

People

  • Herbert E. Durham
  • Max Gruber

Tags

Communities of Interest

  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Animals
  • Antibodies
  • Bacteria
  • Blood
  • Blood Serum
  • Dilution
  • Government (Foreign)
  • Immune Serums
  • Immunity
  • Medical Personnel
  • Precipitation
  • Rodents

Fields of Study

  • Biology

Readers

  • Educational Psychology
  • Microbial Pathology
  • Toxicology/Environmental Toxicology