Marker Frequency Analysis Mapping of the Staphylococcus Aureus Chromosome,
Abstract
Marker frequency analysis of several strains of Staphylococcus aureus has yielded a genomic map supporting the map derived by synchronous chromosomal replication. Gene orders of exponential cells obtained by using reference cells with completed chromosomes effected by chloramphenicol or by phenethyl alcohol treatment were identical, suggesting that these two agents halted chromosomal replication at a common terminus. In several strains, the pantothenate or acriflavine resistance locus changed its relative chromosomal position during exponential growth. The data indicate that more than one chromosomal growing point occurred during logarithmic growth in nonsynthetic medium. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 01, 1970
- Accession Number
- AD0874415
Entities
People
- Robert A. Altenbern