Development of Thermally- and Mechanically-Triggered Self-Immolative Polymers

Abstract

The research program aimed to develop self-immolative polymers (SIPs) that respond to thermal or mechanical energy by transforming fromcovalent polymers into small molecule components with controlled kinetic profiles. Trigger moieties that undergo thermally ormechanochemically driven reactions capable of initiating depolymerization of SIPs are needed for these capabilities. We hypothesized thatoxazine-based moieties can serve as a common motif for entryway into this area. These triggering mechanisms each potentiate passive (e.g.,spontaneous environmental) and on-demand activation of the SIP. This work is an important step toward understanding structure-reactivityrelationships for thermal and mechanochemical SIP triggers.

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Document Details

Document Type
Technical Report
Publication Date
Jul 23, 2015
Accession Number
AD1001054

Entities

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  • Andrew J. Boydston

Organizations

  • University of Washington

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  • Human Systems

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  • Abstracts
  • Agreements
  • Block Copolymers
  • Chemistry
  • Cold Storage
  • Department Of Defense
  • Depolymerization
  • Education
  • Engineering
  • Mathematics
  • Mechanical Energy
  • Molecules
  • Polymers
  • Small Molecules
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  • Students
  • Technology Transfer

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