The Roles of Primary Cilia in Cardiovascular System

Abstract

Hypertension and aneurysm are a prevalent problem in our society. Because the risk of these vascular diseases is too important to ignore, our studies are designed to provide exciting and original concepts to examine the etiologies of hypertension and aneurysm with regard to mechanosensory organelles (primary cilia). Especially within polycystic kidney disease, untreated hypertension can worsen kidney function. Aneurysm rupture in PKD patients also remains a devastating complication that often could result in stroke and death. Our studies therefore aim at investigating new ideas in understanding hypertension and aneurysm formation in PKD.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2015
Accession Number
AD1001441

Entities

People

  • Surya M Nauli

Organizations

  • Chapman University

Tags

DTIC Thesaurus Topics

  • Blood
  • Brain
  • Cardiovascular Diseases
  • Cardiovascular Physiological Phenomena
  • Cardiovascular System
  • Cell Physiological Processes
  • Cells
  • Chemical Synthesis
  • Chemistry
  • Health Services
  • Kidney Diseases
  • Medical Personnel

Fields of Study

  • Medicine

Readers

  • Molecular and Cellular Biology