The Role of Novel Substituted Diindolyl Methane Analogues in the Treatment of Triple-Negative and ErbB2-Positive Breast Cancer

Abstract

The mission of the proposed HBCU/MI Breast Cancer Partnership Training Award at Florida A and MUniversity (FAMU) is to develop a rich intellectual environment that will promote and strengthen the research capabilities of FAMU investigators in the area of breast cancer research. The objectives this proposal are (1) to provide mentorship and training to FAMU researchers in breast cancer research area to enhance the research expertise and competitive ability; (2) to train FAMU investigators through a well defined research project investigating the anticancer potential of C-DIM analogs intreatment of breast cancer; (3) to develop FAMU investigators grantsmanship skills by submitting extramural grants for independent funding; and (4) to create awareness among FAMU researchers and African American Community about breast cancer biology and therapy. The outcome of this proposal will lead to novel oral therapeutic strategies for treatment of triple negative breast cancer (TNBC) and ErbB2-positive breast cancer) EPBC and also result in publications in highly ranked journals. This approach will result in establishment of a successful and independently funded breast cancer research program at FAMU. Our ultimate goal is to become an independent research and training program of excellence for minority investigators.

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Document Details

Document Type
Technical Report
Publication Date
May 01, 2015
Accession Number
AD1001603

Entities

People

  • Mandip S. Sachdeva

Organizations

  • Florida A&M University

Tags

DTIC Thesaurus Topics

  • Antineoplastic Agents
  • Biological Factors
  • Brain
  • Breast Cancer
  • Cancer
  • Cell Physiological Processes
  • Cells
  • Chemistry
  • Enzyme Inhibitors
  • Health Services
  • Lymphocytes
  • Parkinson'S Disease
  • Peptide Growth Factors
  • Peptides
  • Proteins

Readers

  • Oncology (Cancer Research).
  • Research Science/Academic Research