A Randomized, Placebo-Controlled Trial of D-Cycloserine for the Enhancementof Social Skills Training in Pervasive Developmental Disorders

Abstract

The main objective of this application is to determine whether D-Cycloserine (DCS) can enhance the efficacy of social skills training (SST) in the treatment of children and young adolescents with autism spectrum disorders (ASDs). We evaluated the efficacy, tolerability, and last effects of DCS given one hour prior to each of 10 weekly SST sessions forthe treatment of social impairment in 68 children and young adolescents (ages 5-11 years) with ASDs during a randomized placebo-controlled trial. The safety and tolerability of DCS and durability of treatment response was also examined.

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Document Details

Document Type
Technical Report
Publication Date
Nov 01, 2015
Accession Number
AD1001726

Entities

People

  • Marjorie Mccaskey
  • Noha Minshawi-patterson

Organizations

  • Indiana University Health

Tags

DTIC Thesaurus Topics

  • Acquisition
  • Adolescents
  • Age Groups
  • Anxiety Disorders
  • Autism
  • Diseases And Disorders
  • Health Services
  • Information Science
  • Institutional Review Board
  • Medical Personnel
  • Mental Disorders
  • Psychiatry
  • Psychotherapy
  • Standards
  • Statistical Analysis
  • Surveys
  • United States

Fields of Study

  • Medicine
  • Psychology

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