Permethrin Exposure Dosimetry: Biomarkers and Modifiable Factors

Abstract

The primary aim of this project is to investigate the relationship between various modifiable factors and the absorption of permethrin as a result of wearing permethrin-treated Army Combat Uniforms (ACU-Permethrin). The research objective is to examine the effect of body weight/BMI and total energy expenditure on permethrin absorption and dose, as determined by measurement of urinary biomarkers (3PBA and cis- and trans-DCCA) levels. There are two studies involved in our project the first is a study among Army recruits during Basic Training (Study 1) and the second involves Army National Guard Soldiers during Annual Training (Study 2). Approvals and scheduling for Study 1 are complete; data collection will proceed in Oct/Nov 2015. Study 2 data collection will occur in 2016.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2015
Accession Number
AD1001746

Entities

People

  • Susan P. Proctor

Organizations

  • Henry M. Jackson Foundation for the Advancement of Military Medicine

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Absorption
  • Basic Training
  • Biological Markers
  • Biomedical Research
  • Body Weight
  • Contracts
  • Data Analysis
  • Data Management
  • Dosimetry
  • Institutional Review Board
  • Military Training
  • National Guard
  • Public Health
  • Scheduling (Production)
  • Students
  • Training

Readers

  • Clinical Trial Research.
  • Psychological Intervention/Treatment for Stress, Anxiety, PTSD, and Related Emotional and Cognitive Health Symptoms.
  • Toxicology/Environmental Toxicology