Skeletal and Clinical Effects of Exoskeleton-Assisted Gait

Abstract

The purpose of this project is to study the effects on bone health of exoskeleton-assisted gait in individuals with a complete spinal cord injury. Advanced biomechanical models of human locomotion are utilized to estimate the mechanical effects of the dynamic loading of the bone structures that takes place during exoskeleton-assisted gait. The estimated maximum energy equivalent strain is studied as a potential proxy of bone adaptation and correlated with high-resolution peripheral quantitative computed tomography data and with clinical measures (e.g. biomarkers of inflammation such as C-reactive protein and IL-6) that are collected longitudinally. The work carried out by the research team until now has been focused on the development of advanced biomechanical models. The research team is now scheduling data collections in study volunteers to start the experimental part of the project.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2015
Accession Number
AD1002721

Entities

People

  • Karen L Troy
  • Leslie Morse
  • Paolo Bonato

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Biomechanical Phenomena
  • Biomedical Engineering
  • Data Analysis
  • Engineering
  • Exoskeleton
  • Health Services
  • Lower Extremity
  • Mechanical Properties
  • Medical Personnel
  • Professional Development
  • Scheduling (Production)
  • Spinal Cord
  • Spinal Injuries
  • Technology Transfer
  • Tomography
  • Volunteers
  • X-Ray Computed Tomography

Readers

  • Clinical Trial Research.
  • Immunology and Pathology
  • Medical Imaging.