Model Validation for a Noninvasive Arterial Stenosis Detection Problem
Abstract
A current thrust in medical research is the development of a non-invasive method for detection, localization, and characterization of an arterial stenosis (a blockage or partial blockage in an artery). A method has been proposed to detect shear waves in the chest cavity which have been generated by disturbances in the blood flow resulting from a stenosis. In order to develop this methodology further, we use one-dimensional shear wave experimental data from novel acoustic phantoms to validate a corresponding viscoelastic mathematical model. We estimate model parameters which give a good fit (in a sense to be precisely defined) to the experimental data, and use asymptotic error theory to provide confidence intervals for parameter estimates. Finally, since a robust error model is necessary for accurate parameter estimates and confidence analysis, we include a comparison of absolute and relative models for measurement error.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 09, 2013
- Accession Number
- AD1003095
Entities
People
- Carola Kruse
- H. Thomas Banks
- John Whiteman
- M. J. Birch
- M. P. Brewin
- S. E. Greenwald
- Shuhua Hu
- Simon Shaw
- Zachary R. Kenz
Organizations
- North Carolina State University